Generic

> cd ~/Downloads/Xilinx_ISE_DS_Lin_14.7_1015_1
> sudo ./xsetup

Fedora 17 and 20

The cable driver installation will fail on Fedora 17 and 20.

Running ISE

Adding the Xilinx ISE to your PATH seems to cause conflicts so do not do it by default but only when you need to upload the firmware.

Either 
>  PATH=$PATH:/opt/Xilinx/14.7/ISE_DS/ISE/bin/lin64 ; export PATH
or
> source /opt/Xilinx/14.7/ISE_DS/settings64.sh

> /opt/Xilinx/14.7/ISE_DS/ISE/bin/lin64/impact &

Uploading Firmware

See Uploading USBDAQ Firmware for how to upload the firmware.